American Cruise Lines

America’s #1 River Cruise Line

American Cruise Lines carries passengers to the best of America aboard the newest fleet of riverboats and small ships in the United States. Traveling smooth inland waterways and magnificent rivers, destinations include the most historic, culturally unique and scenic areas in the U.S. All departure ports are conveniently located near major airports, creating an easy and relaxing travel experience. Now, with authentic paddlewheelers both in the Pacific Northwest on the Columbia and Snake Rivers and in the American Heartland on the Mississippi River, guests can experience the best of the American rivers in the elegance and comfort of the Queen of the West and the brand new Queen of the Mississippi, the first paddlewheeler of its kind to be built for the Mississippi River in nearly 20 years. Queen of the Mississippi offers a brand new way to experience the longest river system in North America by offering a never-before seen combination of 21st-century technology and first-class amenities, with the historic grandeur of classic American riverboats.

Ships

Start Planning

Deals

  • Kids Jumping Into Pool
    Packages
    Puerto Morelos, Mexico

    Dreams Unfold: Experience Dreams Riviera with Direct Flights from Chicago O'Hare!

    5-7 Nights + Nonstop Airfare from ORD

    Starting from $599

    per person

    5-7 Nights + Nonstop Airfare from ORD

    Starting from $599

    per person

  • Ocean Blue And Sand (26)
    Packages
    Dominican Republic, Caribbean

    Sands of Serenity: Milwaukee's Direct Escape to Ocean Blue & Sand!

    3-7 Nights + Nonstop Airfare from MKE

    Starting from $839

    per person

    3-7 Nights + Nonstop Airfare from MKE

    Starting from $839

    per person

  • Ocean Blue And Sand (27)
    Packages
    Dominican Republic, Caribbean

    Sapphire Shores: Luxurious Getaways to Ocean Blue & Sand from ORD!

    3-7 Nights + Nonstop Airfare from ORD

    Starting from $799

    per person

    3-7 Nights + Nonstop Airfare from ORD

    Starting from $799

    per person