American Cruise Lines

America’s #1 River Cruise Line

American Cruise Lines carries passengers to the best of America aboard the newest fleet of riverboats and small ships in the United States. Traveling smooth inland waterways and magnificent rivers, destinations include the most historic, culturally unique and scenic areas in the U.S. All departure ports are conveniently located near major airports, creating an easy and relaxing travel experience. Now, with authentic paddlewheelers both in the Pacific Northwest on the Columbia and Snake Rivers and in the American Heartland on the Mississippi River, guests can experience the best of the American rivers in the elegance and comfort of the Queen of the West and the brand new Queen of the Mississippi, the first paddlewheeler of its kind to be built for the Mississippi River in nearly 20 years. Queen of the Mississippi offers a brand new way to experience the longest river system in North America by offering a never-before seen combination of 21st-century technology and first-class amenities, with the historic grandeur of classic American riverboats.

Ships

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Deals

  • Cheers
    Packages
    Dominican Republic, Caribbean

    Luxury and Leisure: 7 Nights at Royalton CHIC Punta Cana Plus Airfare from Chicago O'Hare!

    7 Nights + Nonstop Airfare from ORD

    Starting from $1,399

    per person

    7 Nights + Nonstop Airfare from ORD

    Starting from $1,399

    per person

  • Cheers
    Packages
    Dominican Republic, Caribbean

    Luxury and Leisure: 6 Nights at Royalton CHIC Punta Cana Plus Airfare from Chicago O'Hare!

    6 Nights + Nonstop Airfare from ORD

    Starting from $1,229

    per person

    6 Nights + Nonstop Airfare from ORD

    Starting from $1,229

    per person

  • Majestic Colonial Punta Cana (28)
    Packages
    Dominican Republic, Caribbean

    Majestic Getaway: 6 Nights at Majestic Colonial Punta Cana with Flights from Chicago!

    6 Nights + Nonstop Airfare from ORD

    Starting from $1,299

    per person

    6 Nights + Nonstop Airfare from ORD

    Starting from $1,299

    per person